21.1

Biotechnology and genetic modification

Cambridge IGCSE Biology (0610)  · Unit 21: Biotechnology and genetic modification  · 9 flashcards

Biotechnology and genetic modification is topic 21.1 in the Cambridge IGCSE Biology (0610) syllabus , positioned in Unit 21 — Biotechnology and genetic modification , alongside Biotechnology and Genetic modification.  In one line: Biotechnology involves using living organisms or biological systems to develop or make products. Examples include using yeast to brew beer or genetically modified bacteria to produce pharmaceuticals.

This topic is examined in Paper 1 (multiple-choice) and Papers 3/4 (theory), plus Paper 5 or Paper 6 (practical / alternative to practical). Past papers from 2022 to 2025 show this topic across 15 questions worth 221 marks (around 3.3% of all Biology marks in those years).

The deck below contains 9 flashcards — 2 definitions, 3 key concepts, 1 process card and 3 application cards — covering the precise wording mark schemes reward.  Use the 2 definition cards to lock down command-word answers (define, state), then move on to the concept and application cards to handle explain, describe and compare questions.

Key definition

Biotechnology

Biotechnology involves using living organisms or biological systems to develop or make products. Examples include using yeast to brew beer or genetically modified bacteria to produce pharmaceuticals.

What the Cambridge 0610 syllabus says

Official 2026-2028 spec

These are the exact learning objectives Cambridge sets for this topic. Match the command word (Describe, Explain, State, etc.) in your answer to score full marks.

  1. State State that bacteria are useful in biotechnology and genetic modification due to their rapid reproduction rate and their ability to make complex molecules
  2. Discuss Discuss why bacteria are useful in biotechnology and genetic modification, limited to: (a) few ethical concerns over their manipulation and growth (b) the presence of plasmids Supplement
Key Concept Flip

Why are bacteria useful in biotechnology due to their reproduction rate?

Answer Flip

Bacteria reproduce rapidly (binary fission), enabling faster production of desired substances. For instance, genetically modified bacteria can quickly produce large quantities of insulin for diabetic patients.

Key Concept Flip

State two reasons bacteria are useful in biotechnology and genetic modification, as related to ethical concerns.

Answer Flip

Bacteria raise fewer ethical concerns because they are single-celled and lack a complex nervous system. This simplifies research and development. Unlike manipulating animal cells, there is less debate surrounding the suffering of bacteria.

Key Concept Flip

What role do plasmids play in genetic modification?

Answer Flip

Plasmids are small, circular DNA molecules in bacteria that can be easily modified and transferred to other bacteria.

Example: plasmids can carry the gene for human insulin into bacteria, creating genetically modified bacteria that can produce insulin.
Key Concept Flip

Explain why the ability to make complex molecules makes bacteria useful in biotechnology.

Answer Flip

Bacteria can be genetically engineered to produce complex molecules, such as antibiotics or enzymes, that are difficult or expensive to synthesize chemically. An example is using *E. coli* to produce the enzyme amylase for food processing.

Definition Flip

What is biotechnology?

Answer Flip

Biotechnology involves using living organisms or biological systems to develop or make products. Examples include using yeast to brew beer or genetically modified bacteria to produce pharmaceuticals.

Definition Flip

Define genetic modification.

Answer Flip

Genetic modification involves altering the genes of an organism. An example is inserting a gene for pest resistance from *Bacillus thuringiensis* into maize plants to reduce the need for pesticides.

Key Concept Flip

Give a specific example of how bacteria are used to produce a medically important product.

Answer Flip

Genetically modified *E. coli* bacteria are used to produce human insulin. The human insulin gene is inserted into the bacterial plasmid, which then directs the bacteria to synthesize insulin, used to treat diabetes.

Key Concept Flip

How is the presence of plasmids in bacteria advantageous for producing vaccines?

Answer Flip

Plasmids can be used to insert genes coding for specific antigens from pathogens into bacteria. These bacteria then produce the antigen, which can be purified and used as a subunit vaccine.

Example: Hepatitis B vaccine production.
Key Concept Flip

Describe how bacteria can be used to produce biofuels.

Answer Flip

Certain bacteria, such as cyanobacteria, can be genetically modified to produce biofuels like ethanol or biodiesel. These bacteria can convert biomass or CO2 into fuels. This offers a sustainable energy alternative.

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20.4 Conservation 21.2 Biotechnology

Key Questions: Biotechnology and genetic modification

What is biotechnology?

Biotechnology involves using living organisms or biological systems to develop or make products. Examples include using yeast to brew beer or genetically modified bacteria to produce pharmaceuticals.

Define genetic modification.

Genetic modification involves altering the genes of an organism. An example is inserting a gene for pest resistance from *Bacillus thuringiensis* into maize plants to reduce the need for pesticides.

Tips to avoid common mistakes in Biotechnology and genetic modification

More topics in Unit 21 — Biotechnology and genetic modification

Biotechnology and genetic modification sits alongside these Biology decks in the same syllabus unit. Each uses the same spaced-repetition system, so progress in one informs the next.

Cambridge syllabus keywords to use in your answers

These are the official Cambridge 0610 terms tagged to this section. Mark schemes credit responses that use the exact term — weave them into your answers verbatim rather than paraphrasing.

biotechnology genetic modification genetic engineering GM GMO transgenic recombinant DNA restriction enzyme ligase plasmid vector insulin bacteria fermentation fermenter bioreactor enzyme pectinase biological washing powder yeast bread beer wine yoghurt cheese

Key terms covered in this Biotechnology and genetic modification deck

Every term below is defined in the flashcards above. Use the list as a quick recall test before your exam — if you can't define one of these in your own words, flip back to that card.

Biotechnology
Genetic modification

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How to study this Biotechnology and genetic modification deck

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